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Cialis (tadalafil) is a type of PDE5 inhibitor that the Food and Drug Administration approved in 2024. Like other PDE5 inhibitors, it increases blood flow to the penis. There are two different ways to take Cialis: as needed or daily. If you take the pill daily, the medication stays in your system constantly. The typical dose is 10 mg for occasional use and 2.5 or 5 mg for daily use. The typical maximum dose of Cialis for ED is 20 mg once a day. Be consistent for daily use. Some people prefer the cialis dosage daily use instructions Cialis can cost around $300 to $400 per month out of pocket, depending on the dosage you need. The first generic version of Cialis was released in October 2024, and other manufacturers have released generic versions since then. This has increased market competition, driving prices down. Tadalafil (Cialis) is one of the most popular erectile dysfunction (ED) drugs. Its major appeal? The drug comes in low-dose versions that can be taken daily. This means you can have sex at any time, rather than needing to take a pill from time to time as needed like other ED brands. The starting dose for daily-use Cialis is 2.5 milligrams (mg). As needed for ED: 5 to 20 mg by mouth as a one-time dose, with a maximum of one dose in 24 hours. Effects may last up to 36 hours. Daily dosing for ED: 2.5 or 5 mg by mouth daily. For daily dosing, the maximum dose is 5 mg per day.